These 4 fertility doctors all went through IVF. Here’s what they learned.

Written by Blog Admin
17 Jul

This article first appeared in Fairfax media July 2017

Fertility specialist Dr Julianne Cameron, 42, has a three year old son who was conceived naturally and is currently 25 weeks pregnant with a girl conceived via IVF.

“Our son was six months old when we started trying for another baby. I fell pregnant within a month but miscarried. After that, I miscarried a further three times.

I knew that wasn’t normal and thought it may be a problem with chromosomes. I was conscious of my age, and didn’t want to keep wasting time, so I organised to do IVF so that the embryos could be screened. I did six stimulated cycles in total and had six egg collections. I’d respond well to the IVF cycles, with a high number of eggs and fertilised embryos. But, as I suspected, the embryos were abnormal and transferring them would end in miscarriage.

It was heartbreaking to get to day five only to find out that the embryos were all abnormal. Initially I wanted to get three normal embryos in total before I transferred any, as I wanted to freeze the others for the future. But, as time went on I figured I’d be happy with just one.  The last cycle I ended up with two viable embryos. One was transferred (this pregnancy), and the other is frozen.

For me, going through IVF wasn’t that bad. But going through miscarriage was awful and gave me an insight into how many of my patients feel. Miscarriages are still taboo, but I understand the grieving process and know what care and support people need. I also offer those patients extra monitoring throughout that first trimester to help relieve anxiety. Most of my patients know about my miscarriages and IVF. It helps to reassure them that pregnancy does happen and they relax because they know I can relate. At this stage I would like to go back for a third child. But, this second baby could give me a rude awakening. Perhaps ask me again in 18 months.

Dr Fleur Cattrell, 44, is a fertility specialist. Her 13-year-old daughter was conceived via IVF.

I was working as a junior fertility consultant when I realised I was going to need help to conceive. We’d been trying for a while and my ongoing symptoms pointed to endometriosis. After diagnosis and treatment, I still didn’t fall pregnant naturally. I was going to have to do IVF, but seeking help was so hard because all the specialists were my colleagues.

I felt a responsibility to self-diagnose and self-treat. I even took some ovulation tablets in a desperate attempt to avoid telling my colleagues or making that specialist appointment. Eventually I broke down and admitted to a colleague that I needed help. Soon after that I started IVF.

At the time, I was training to become a Reproductive Endocrinology and Infertility specialist. Going through the treatment I was worried that I might have to change careers, as being faced with it every day was very traumatic. I wanted to say to the patients, “I’m doing IVF too, I know how you feel”, but I would have cried at work. I found that I coped physically with the process but, emotionally, I was a wreck. I never got a break from the sadness because infertility was all around. I managed to keep professional and never told patients my situation, and still don’t. It’s not relevant to them and I don’t want them to compare themselves to me. Everyone’s experience is different.

From a professional viewpoint, IVF has helped me empathise and connect with patients on a different level. It makes my job even more fulfilling. I know that the emotion and chronic sadness is like nothing else you’ve ever known.  I vowed at the time I would never forget that feeling. I haven’t and I won’t.

Dr Kokum Jayasinghe is a fertility specialist and gynaecologist. She has two sons, aged nine and six, who were both conceived via IVF.

I was 30 and undergoing my obstetric training when I realised I needed help to conceive.  We’d been trying for 12 months and, because I practice what I preach, I went to see a fertility specialist.

I was diagnosed with unexplained infertility which was frustrating. I experienced anxiety because I like to be in control and with this I wasn’t.  But with my training I also knew this diagnosis meant that things were normal so there’d be a good chance of success. I was treated by a specialist that I’d looked up to during my training.  I knew that she was warm, empathetic and supportive.

I was one of the extremely lucky ones. I had one egg pick and two embryo transfers and two sons. We always wanted two so we feel really blessed. When I started IVF I was still going through my obstetrician and gynaecology training but hadn’t made my mind up about a sub speciality.  My own experience helped me decide to become a fertility specialist. It helped me understand that it’s not just the facts and stats when you go through the treatment, there’s a human and emotional side too.

I do sometimes share my experience with my patients depending on their situation.  If they’re on repetitive cycles, losing faith and need extra care, I look them in the eyes and say, “I know that you’re going through”, and I mean it. I open up and I can see that it helps.

The best part of my job is helping others. There’s nothing better than seeing couples come in with their children or sending pictures of their baby. It’s such a privilege to help them achieve their dreams and to know I’ve been part of it.

Dr Melissa Cameron, 44, is a fertility specialist. With her partner, she used a donor to conceive their children, a nine year old boy and a six year old girl.  She carried their second child.

I’ve been with my partner for nearly 17 years and we’d always talked about having children.

We started looking into it after being together for five years. It took us a year to go through the pros and cons of different donor situations. We explored the idea of a clinic recruited donor, but decided that having a known donor suited us better. Our known donor is a good friend who my partner went to university with, and I’ve known him as long as I’ve known her.

My partner carried our first child, and myself the second. We’d always planned on this and were very fortunate that it worked out that way. I didn’t have to go through IVF, only IUI (Intrauterine insemination). I had unstimulated IUI cycles and conceived very quickly, only needing to do three cycles. The hardest thing for me about going through it was having to share the intimate details of my life with colleagues. It wasn’t the medical details so much as more to do with pregnancy planning and how would that affect working.

It’s much harder being a patient than a doctor. As a doctor, we’re generally in control, and have professional distance from the situation. As a patient, you have very little control and are in the midst of it, experiencing all the up and down emotions that go with trying to conceive. I definitely have a better understanding and empathy towards patient situations now, especially experiencing some of the day to day annoyances, such as trying to fit appointments in and juggling things.


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Post mortem sperm retrieval – a matter of life and death

Further to his interview on Channel 9’s 60 minutes programme, Dr Ben Kroon of Queensland Fertility Group discusses the topic of post mortem sperm retrieval.

Thankfully for the vast majority of people, post mortem sperm retrieval will never become a reality.

It is an extremely complex and challenging area of reproductive medicine, involving retrieval of sperm after a man’s death so that it can be used by his surviving partner.

While new assisted reproductive technologies are allowing more people than ever to fall pregnant and start the family they desire, the law, at times, does not keep pace with these developments.

In Australia, the law does not specifically address the issue of retrieval and use of sperm after a man’s death. So, while a partner may be sure she knows what her partner ‘would have wanted’, without supporting legal documents explicitly stating those wishes, the question of retrieval and use of sperm is not clear.

In most cases, an urgent court order is needed to retrieve sperm. This is a problem because while the judge is coming to a decision, every hour that the sperm lies in the body after death decreases the chance of finding live sperm.

While 24 hours is the accepted time period for successful retrieval, there may still be a small chance up to 36 hours after death.  However, while retrieval might be medically successful, the court may never permit a woman to use the sperm.

I co-authored a paper, published in the Australian and New Zealand Journal of Obstetrics and Gynaecology, in which we surveyed 28 IVF clinics across Australasia to test attitudes towards posthumous sperm retrieval and use.

It appears that directors of IVF units are generally supportive of the practice, given the right circumstances, but that the lack of clear laws makes the response to requests for sperm retrieval very difficult.

Myself, and the papers co-authors, believe that ‘clear, accessible and consistent law in this area would benefit everyone involved, including the medical, legal and societal stakeholders’.

It is not only the law that needs to catch up. In the same way that people discuss organ donation, I believe that couples should discuss post mortem sperm use.

Men should consider and discuss with their partners whether they would want to father a child after their death, bearing in mind that they could not raise the child, and that the child could conceivably be raised by another man.

I need to be clear that I am not suggesting that more people should have their sperm collected and used after their death.

Personally, I wouldn’t want my sperm to be retrieved and used if I died suddenly, and my wife knows this. But, if couples don’t have the discussion and document their wishes, it is seldom clear what one would have wanted if one dies.

Have you considered discussing post mortem sperm retrieval with your partner?

Blog Admin
17 Jul

Children of IVF parents as healthy as those conceived spontaneously

In 2007 a local Melbourne paediatrician approached me curious about whether girls conceived through In-Vitro Fertilisation (IVF) and other Assisted Reproductive Treatments (ART) enter puberty earlier than those conceived spontaneously. With the first babies born through IVF now reaching their mid-30s, this query was my early motivation and the catalyst to initiate a study on the effects of IVF and ART on the health and wellbeing of children conceived through these technologies.

How healthy are IVF children?

This project was the largest of its kind ever attempted, worldwide.

We found that children conceived by IVF grew into healthy, normal adults when compared to children conceived spontaneously.

The collaborative study initially funded by Melbourne IVF prior to a National Health and Medical Research Council (NHMRC) grant involved researchers from Murdoch Children’s Research Institute, Monash IVF, the University of Melbourne and Monash University. Interviewing 656 mothers who used ART and their 547 young adult offspring aged between 18 and 29 years, and compared this to reports from 868 mothers and their 549 young adult offspring who were conceived spontaneously.

Self-report of their health and wellbeing for the first 18 years of life found the ART children had a normal body mass index and similar history of pubertal development to those spontaneously conceived. Educational outcomes, including tertiary admission ranked scores and completion of tertiary education, were also similar.

Were there differences in the health of IVF-conceived children?

Mothers did report a higher rate of hospitalisation, as well as a higher rate of asthma and hay fever in ART children. We found this to be in line with what we already know as a common mild condition in the whole community. The rate is not much higher at 23% of spontaneously conceived children experiencing allergies, compared to 30% of ART children.

These problems are more common in premature babies and we know a higher proportion of ART babies are born prematurely for reasons still largely unknown. Premature births may be because of the age of IVF mothers, as having a baby in your early 40s is generally harder than having a baby in your late 20s or early 30s.

ART parents might take their children to the GP more often and consequently they are diagnosed at a higher rate. We found ourselves speculating if parents of IVF-conceived children are more protective reducing their baby’s exposure to dust and dirt in turn increasing their risk factor for later allergies.

The finding of increased hospitalisations, including in the secondary school years, has not been examined in other studies to date and the reasons for hospitalisation varied, with no consistent set of conditions. Again, we wonder if this is due to parental vigilance.

What will be done to investigate further?

This study fills an important gap in our knowledge about the long term health outcomes of children conceived via IVF and ART. Our results indicate that the perceived physical, mental health, social and environmental quality of life reported by the 547 ART-conceived adults is very similar to that of their non-ART conceived peers.

We have a responsibility to continue this research and gather further clinical review in long term follow up of those conceived through IVF and other ART. Further research will evaluate their health status and follow up to determine if there are any important lifelong medical or other legacies of IVF.

What does this mean for those considering IVF?

This study provides reassurance to those requiring IVF that there are no apparent substantial negative long term health and wellbeing effects on young adults compared to those spontaneously conceived.

This study is published in Fertility and Sterility. 

Learn more about IVF in Queensland, Victoria and New South Wales.


Blog Admin
17 Jul

15 years of IVF patients – how have women changed?

The media is increasingly full of stories showcasing the latest 50 year old mum, or the celebrity who has undergone IVF. Even women who have used donor eggs are increasingly more comfortable discussing their medical history.

But, do these sensationalised stories really reflect the changing face of the IVF patient we see every day at our fertility clinic?

At Queensland Fertility Group Toowoomba we decided to assess the reality of these changes. In order to do this we conducted a retrospective study of 1587 women who had undergone IVF between 1998 and 2013 at our clinic in Toowoomba (based in the Darling Downs, west of Brisbane). We know that during this time there has been considerable social change, and we were interested to see how our patients may correspondingly have changed during this 15 year period.

Older women

Studies carried out by the Australian Institute of Health and Welfare informs us that the average age of women receiving treatment using their own eggs or embryos, is 36 years. We know too that over the last 20 years the average age of women giving birth has increased by 7.5%.

What did our study of 1,587 women show? The average age of women undergoing IVF treatment in Toowoomba has significantly increased by 6% - from 33 years in 1998 to 35 years in 2013.  Interestingly, the major shift has been the marked increase in the number of women aged over 39 completing treatment - which 15 years ago was just 3% and by 2013 had grown to 18%.

Rising obesity

The number of overweight and obese Australians has been gradually increasing for the past 30 years across all demographics – from wealthy, metropolitan suburbs to rural and disadvantaged communities.

An Australian Bureau of Statistics Australian Health Survey identified that between 1995 and 2011/12 the average adult woman’s weight had increased by 4kgs. The report likewise stated that in 2011/12 27% of all females aged 18 and over were overweight with a Body Mass Index (BMI) of 25 to 30.

Toowoomba is no exception to this trend. It’s therefore not surprising that the average IVF patient has become heavier. Women undergoing IVF treatment in 1998 at QFG Toowoomba had an average weight of 66kgs, and this had increased up to 77kgs by 2013. More significantly, their BMI (which also takes into account their height) moved from normal at 24 to overweight at 28 in 2013.

Single Women and Same-sex Couples

Shifts have occurred in the structure of families and as a result, we have seen a considerable increase over the past five years in single and same-sex couples accessing donor sperm to start their families.

Looking at the subset of patients where female cause was the sole reason for them having treatment, the proportion of single women and same-sex couples undergoing IVF increased from 2% in 2008 to 22% in 2013.

15 years later

Women attending our fertility clinic in 2013 are significantly older, heavier and have an increased BMI than they did in 1998. However, as women delay child bearing, by choice or circumstance, we need to ensure that there isn’t an unrealistic expectation that medical science can undo the effects of age.

What would you advise?

Unfortunately, we still cannot reverse the aging process, but we can ensure women are given the correct information to help them make informed decisions earlier. For example, the increasing use of the Anti-Mullerian Hormone (AMH) test or as it's more widely known, the egg timer test, can help a Fertility Specialist better assess a woman’s fertility and guide the direction of her fertility treatment.

Many women still remain unaware of the effect of weight on their fertility. We advise weight loss with simple lifestyle changes and, if necessary, dietician support. In addition to boosting a woman’s natural fertility, this can also have a beneficial impact on pregnancy and the health of the child.

This data was presented by Leita Fien, Fertility Nurse, Toowoomba at the 5th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2014) in conjunction with the Fertility Society of Australia Annual Conference held in Brisbane April 4-6, 2014.  Leita would like to acknowledge and thank her co-authors and colleagues Susan Lax, Julie Logan, Jeremy Osborn, and Dr John Esler, Clinical Director QFG Toowoomba.

Blog Admin
17 Jul

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